Prostate Cancer Resource Center
Q & A Cases from The Bethesda Review of Oncology
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A 63- year- old with metastatic castration- resistant prostate cancer has a rising PSA despite castrate levels of testosterone. He has previously been treated with only androgen deprivation therapy and now seeks additional systemic therapy. His past medical history includes hypertension, hyperlipidemia, and a cerebral vascular accident 8 months ago with minor residual neurological defects. Which of the following therapies is least appropriate for this patient?

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A 63- year- old male with metastatic castration- resistant prostate cancer (metastatic to the scapula and 3 ribs) is currently being treated with ADT and enzalutamide 160 mg/ daily. 

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A 65- year- old male with mCRPC including metastasis to the pelvis, spine, and ribs has recently started treatment with enzalutamide. 

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A patient is seeing you in follow- up for his mCPRC including metastasis to the lungs, liver, and spine. 

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